Cross-study synthesis
Study Comparison
Align cohorts, follow-up periods, complication definitions, and patient-reported outcomes before synthesis.
Comparison set
Reconstruction type
Primary endpoint
Reoperation
Standard window
24 months
Outcome matrix
Autologous and implant-based reconstruction cohorts
| Study | Cohort | n | Follow-up | Total loss | Reoperation | BREAST-Q Δ | Certainty |
|---|---|---|---|---|---|---|---|
| AR-042 | DIEP | 214 | 24 mo | 0.9% | 7.5% | +18.4 | Moderate |
| AR-031 | DIEP | 168 | 18 mo | 1.2% | 8.9% | +15.1 | Moderate |
| AR-024 | MS-TRAM | 126 | 24 mo | 1.6% | 10.3% | +13.7 | Low |
| AR-016 | Implant | 241 | 36 mo | — | 18.7% | +8.9 | Low |
Definition alignment
Flap loss
4/4 studies alignedReoperation
3/4 studies alignedMajor complication
2 definitionsSynthesis readiness
4
Eligible
1
Needs mapping
2
Excluded